EV71 3C protease induces apoptosis by cleavage of hnRNP A1 to promote apaf-1 translation.
Enterovirus 71 (EV71) induces apoptosis to promote viral particle release.Earlier work showed that EV71 utilizes its 3C protease to induce apoptosis in a caspase-3-dependent pathway, though Hidden the mechanism is unknown.However, work from Vagner, Holcik and colleagues showed that host protein heterogeneous ribonucleoprotein A1 (hnRNP A1) binds th